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Nnyocha ndị otu nyocha sayensị Canada bipụtara na nso nso a na-atụ aro na cannabinoids nwere ike rụọ ọrụ na igbochi na ịgwọ COVID-19 na ogologo oge COVID.

Na nyocha zuru oke, otu ndị sayensị Canada na-enye nghọta na-atọ ụtọ banyere ọrụ cannabinoids nwere n'ịlụso nje COVID-19 ọgụ.Ọmụmụ ihe a, akpọrọ "Cannabinoids na Endocannabinoid System na Early SARS-CoV-2 na ndị ọrịa COVID-19 na-adịghị ala ala," bụ Cassidy Scott, Stefan Hall, Juan Zhou, Christian Lehmann na ndị ọzọ dere wee bipụta ya na Journal of SARS-CoV. -2 ″ magazin.

Ọgwụ Clinical.Site n'inyocha ọtụtụ data sitere na ọmụmụ gara aga, akụkọ ahụ tụlere ka akụkụ nke osisi cannabis nwere ike isi rụọ ọrụ dị mkpa n'igbochi mmalite nke COVID-19 na ibelata mmetụta ya na-adịte aka.Nchoputa a na-egosi na cannabinoids, ọkachasị ndị ewepụtara na osisi cannabis, nwere ike igbochi ịbanye n'ime sel, belata nrụgide oxidative na-emerụ ahụ, ma gbochie nzaghachi mgbochi na-egbu egbu na-ahụkarị n'ọnọdụ ndị siri ike.Ọmụmụ ihe ahụ gosikwara ike ọrụ cannabinoids nwere n'ịgbasa mgbaàmà dị iche iche na-aga n'ihu nke ogologo oge COVID-19.

Dabere na ọmụmụ ahụ, cannabinoids nwere ikike igbochi ịbanye nje virus, ibelata nrụgide oxidative na ibelata oke ifufe cytokine metụtara nje COVID-19.Nnyocha na-egosi na kpọmkwemcannabinoid wepụnwere ike belata ọkwa nke angiotensin-converting enzyme 2 (ACE2) na anụ ahụ isi, si otú a na-egbochi nje ịbanye na sel mmadụ.Ndị nyocha ahụ kwuru na nke a dị oke mkpa nyere ọrụ ACE2 dị ka ọnụ ụzọ izizi maka ntinye nje.Akụkọ ahụ tụlekwara ọrụ cannabinoids n'ịgbasa nrụgide oxidative, ihe dị mkpa na pathogenesis nke COVID-19.

Site n'ịtụgharị free radicals n'ime obere reactive ụdị, cannabinoids dị kaCBDnwere ike inye aka belata mmetụta ọjọọ nke nrụgide oxidative n'ọnọdụ siri ike nke COVID-19.Dị ka ọmụmụ ahụ si kwuo, cannabinoids nwekwara ike inwe mmetụta bara uru na oké ifufe cytokine, nzaghachi mgbochi siri ike nke COVID-19 kpatara.E gosiputara Cannabinoids ka ọ dị irè n'ibelata cytokines na-akpasu iwe, na-atụ aro ikike ha nwere ijikwa nzaghachi mgbochi ndị dị otú ahụ.

Ogologo COVID na-ezo aka na ọnọdụ na-emekarị ka COVID-19 na-atụgharị gaa na ọkwa na-adịghị ala ala.Nnyocha ahụ na-ekpughe ikike nke cannabinoids n'ịgwọ mgbaàmà na-aga n'ihu nke ịda mbà n'obi, nchekasị, nsogbu nrụgide post-traumatic, ehighi ura, mgbu na ọnwụ nke agụụ.Usoro endocannabinoid na-ekere òkè na mmekọrịta nke usoro ụjọ dị iche iche, na-eme ka ọ bụrụ ihe mgbaru ọsọ maka ọgwụgwọ nke mgbaàmà neuropsychiatric ndị a.

Ọmụmụ ihe a nyochakwara ụzọ dị iche iche oriri na ụdị ngwaahịa cannabis dị iche iche nke ndị na-azụ ahịa na-eji.Nnyocha na-egosi na ntinye site na iku ume nwere ike inwe mmetụta ọjọọ na ndị nwere ọnọdụ iku ume, na-egbochi mmetụta ọgwụgwọ ya."Ọ bụ ezie na ị smokingụ sịga na vaping na-abụkarị ụzọ kachasị amasị ndị ọrịa cannabis n'ihi na ha na-amalite ngwa ngwa, uru ọgwụgwọ cannabinoid nwere ike ịkwụsị site na mmetụta ọjọọ nke iku ume iku ume na ahụike iku ume," ndị nyocha ahụ kwuru.Nnyocha na-egosi "Ndị ọrịa na-eji vaporization cannabis na-enweta obere mgbaàmà iku ume karịa ise siga n'ihi na ngwaọrụ vaporizer anaghị ekpo ọkụ cannabis ruo n'ókè nke ọkụ."Ndị dere akụkọ ahụ na-ekwusi ike mkpa ọ dị maka nyocha ọzọ na mpaghara a.Ọ bụ ezie na nchoputa nke mbụ na-agba ume, ha na-adọ aka ná ntị na ha bụ nke mmalite na sitere na ọmụmụ ihe na-abụghị kpọmkwem na COVID-19.Ya mere, ọmụmụ ihe ezubere iche na nke zuru oke, gụnyere nnwale ụlọ ọgwụ, dị oke mkpa iji ghọta nke ọma ọrụ na ịdị irè nke cannabinoids n'ịgwọ ọrịa SARS-CoV-2 n'oge na nnukwu oge.Ọzọkwa, ndị na-ede akwụkwọ na-akwado maka nyocha miri emi karị na nkà mmụta ọgwụ na ọgwụ nwere ike ịgwọ ọrịa nke usoro endocannabinoid ma na-agba ndị ọkà mmụta sayensị ume ka ha nyochaa usoro a.